Chronic Inflammation Links Cancer and Parkinson’s Disease
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چکیده
منابع مشابه
Chronic Inflammation Links Cancer and Parkinson’s Disease
An increasing number of genetic studies suggest that the pathogenesis of Parkinson's disease (PD) and cancer share common genes, pathways, and mechanisms. Despite a disruption in a wide range of similar biological processes, the end result is very different: uncontrolled proliferation and early neurodegeneration. Thus, the links between the molecular mechanisms that cause PD and cancer remain t...
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Since its initial discovery in Drosophila, Hedgehog (HH) signaling has long been associated with foregut development. The mammalian genome expresses 3 HH ligands, with sonic hedgehog (SHH) levels highest in the mucosa of the embryonic foregut. More recently, interest in the pathway has shifted to improving our understanding of its role in gastrointestinal cancers. The use of reporter mice prove...
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ژورنال
عنوان ژورنال: Frontiers in Aging Neuroscience
سال: 2016
ISSN: 1663-4365
DOI: 10.3389/fnagi.2016.00126